Influence of AQP 1 on cell adhesion , migration and tumor sphere formation 1 in malignant pleural mesothelioma is substratum and histological type
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چکیده
Influence of AQP1 on cell adhesion, migration and tumor sphere formation 1 in malignant pleural mesothelioma is substratum and histological type 2 dependent 3 4 Rajesh M. Jagirdar, Eleni Apostolidou, Paschalis Adam Molyvdas, 5 Konstantinos I. Gourgoulianis, Chrissi Hatzoglou, Sotirios G. Zarogiannis 6 7 8 Department of Physiology, Faculty of Medicine, University of Thessaly, 9 BIOPOLIS, Larissa, 41500, Greece 10 Department of Respiratory Medicine, Faculty of Medicine, University of Thessaly, 11 BIOPOLIS, Larissa, 41500, Greece 12 13 14 Running Title: AQP1 influence on MPM cell phenotypes 15 16 17 *Corresponding author: 18 Sotirios G. Zarogiannis, Ph.D., M.P.H., Environmental Pleural & Lung Diseases 19 Group, Department of Physiology, Faculty of Medicine, University of Thessaly, 3 20 Panepistimiou Str., BIOPOLIS, Larissa 41500, Greece. Tel: +3
منابع مشابه
Influence of AQP1 on cell adhesion, migration, and tumor sphere formation in malignant pleural mesothelioma is substratum- and histological-type dependent.
Malignant pleural mesothelioma (MPM) is an aggressive cancer. MPM cells express aquaporin-1 (AQP1) that in other cancers has been shown to participate in the tumor metastasis processes. However, in MPM patients AQP1 overexpression is an independent prognostic factor favoring survival. In this study we aimed at evaluating the role of AQP1 in cell adhesion, migration, and tumor sphere formation i...
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